On 30 Jul 2018, at 04:06, sunp <[log in to unmask]> wrote:

Hi FSL experts,

I had a question I was hoping you could help me with. This involves functional correlation of ROI regions.
After performing MELODIC, I got MELODIC_IC as output.  These included 20 Independent components. The output of melodic, MELODIC_IC, was used as my ROI's for all the subjects (700 of them).

However, the issue here is that the MELODIC_IC doesn't necessarily have an accurate representation of the location of the ROI's for all of my datasets.
For instance, one subject might have a smaller sized brain, where some of the ROI's may not have any temporal data at all associated with it (because they fall outside of the brain).  Whereas another brain could be larger in size so the ROI regions cover the brain well, and we get temporal values.

This can be problematic when I come to do my calculations to study functional correlations.  Any suggestions on what I can do to fix this?

How can I get an ROI mask that can correctly represent all my data (700 subjects)? In other words, I dont want any ROI's to have zero temporal values because they fall outside of the brain region.  How can I correct that?

I'm not sure if this is a registration issue or what exactly.

Any help would be appreciated.

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