Dear experts, I am attempting to assess the effects of age on vertex-wise grey/white-matter contrast, after regressing out effects of sex and vertex-wise effects of thickness using the -evperdat flag. My setup for the left hemisphere is as follows: # Configuration file for PALM. # Version alpha105, running in MATLAB 8.3.0.532 (R2014a). -i path/concat_n1467_lh.contrast.10.mgh -evperdat path/concat_n1467_lh.thickness.15.mgh 4 -s path/freesurfer_5.3.0/subjects/fsaverage/surf/lh.white -T -tfce2D -logp -d path/age_reg.sex.thick_design.csv -t path/contrast.csv -n 10.000 -o path/lh_contrast_fsaverage.10.age_reg.sex.thick -demean -fdr -“i” is a single .mgh file containing 1467 concatenated contrast surfaces -“evperdat” is a single .mgh file containing 1467 concatenated thickness surfaces My design matrix contains 1467 rows and 4 colomns (1st for male, 2nd for female, 3rd for age and a 4th which is a dummy variable for thickness containing 0’es (I have also tried other values here). My contrast is as follows: 0,0,1,0 0,0,-1,0 The error I receive is : {Error using zeros Out of memory. Type HELP MEMORY for your options. Error in palm_core (line 615) plm.Hz{y}{m}{c}{o} = zeros(N,N,size(plm.Mset{m},3)); Error in palm (line 81) palm_core(varargin{:}); } I was wondering if this really seems to be a memory problem, or if more likely, I have set it up incorrectly? Thank you all so much in advance! Kind regards Linn Norbom ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1