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Dear Colleagues
Our lab uses the Roche Total PSA assay (04491734190) and the kit insert states the following with respect to Limits and ranges [CLSI EP17-A]:
Measuring range 0.003 – 100 ng/mL
Lower detection Limit 0.003 ng/mL
Limit of Blank 0.006 ng/mL
Limit of Detection 0.014 ng/mL
At present we report our Total PSAs to one decimal place and report any results less than 0.1 as <0.1 ug/L.
[Our lowest IQC (BioRad Lyphochek) has a target value of 0.1 and runs with a CV of just under 6%]
We are getting an increasing number of requests to report down to much lower values.
I was wondering what other Roche users report down to? And indeed what users of other assays do?
Regards
Mark Lynch
Altnagelvin Hospital
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