*To treat pain better, we should attend to these complex patients, rather than exclude them. More such pragmatic clinical trials are needed. We need to incorporate psychology and complexities into clinical trials and medical care.* Ante el dolor, una respuesta integral (más allá de la biología). Y ensayos clínicos que permitan el análisis de la complejidad). https://www.nature.com/articles/d41586-018-04994-5?utm_source=twt_na&utm_medium=social&utm_campaign=NNPnature -un saludo juan gérvas @JuanGrvas