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Hi,

This sounds fine if you are just using the PVE to restrict your ROI to gray matter.

All the best,
	Mark


> On 14 Aug 2017, at 12:23, Yasmine Fathy <[log in to unmask]> wrote:
> 
> Hi Mark,
> 
> Sorry about the confusion again. 
> 
> I am multiplying my ROI (which is grey matter) by sienax pve_1 mask. The aim was to make the ROI fit within the grey matter region as much as possible.
> 
> So, I thresholded and binarized pve_1 and multipled by my grey matter ROI then transferred it to DTI space.
> 
> I hope this is clearer. Would you recommend this approach?
> 
> Thanks.
> 
> Best,