Dear Maaly and Rouhollah, given that you are using SPM12, the simplest would be to change spm_defaults.m line 49 such that it reads: defaults.mat.format = '-v7.3'; or, better, create a file called spm_my_defaults.m in your MATLAB path containing: global defaults defaults.mat.format = '-v7.3'; Also, note that, if you have already specified first-level models for each subject (i.e. you have individual SPM.mat files), then you can create a fixed-effect model automatically with the batch module: SPM > Stats > Mixed-effects (MFX) analysis > FFX Specification (provided all subjects have the same number of parameters for each session). Best regards, Guillaume. On 03/07/16 14:27, Rouhollah Abdollahi wrote: > Dear Maaly > > "help save" says that you need to have 64-Bit operating system. Do you > run Matlab on 64 Bit ? > you can also check which version SPM is using for save by using: > *spm_get_defaults('mat.format'), *for me it shows -v6 > > if not then you may change line 732 in "spm_spm.m" using > > save( 'SPM.mat', SPM , '-v7.3' ) > > Best Regards > Rouhollah Abdollahi > > *Institut für Neurowissenschaften und Medizin (INM-3)* > Forschungszentrum Jülich > Leo-Brandt-Straße > 52425 Jülich, Germany > > Tel: +49 2461 61-9324 > > > > > On Sun, Jul 3, 2016 at 3:13 PM, Maaly Nassar > <[log in to unmask] > <mailto:[log in to unmask]>> wrote: > > Dear Rouhollah > > The problem is that I did change the preferences and I'm still > getting this warning (attached image) and the SPM.mat file still > can't be saved after estimating the model. do you know a way to > override spm original saving code? so on executing "writing spm" > function, -v7.3 is used instead. > > Thanks, > > maaly > > -- Guillaume Flandin, PhD Wellcome Trust Centre for Neuroimaging University College London 12 Queen Square London WC1N 3BG