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You want to analyze each tissue class in separate models. 

A template is something you create to be able to map everything into a common space (e.g. MNI). This isn't done with statistics. In the case of analysis of all 3 classes, you could just overlay your significant results on the same underlay using FIVE.

Best Regards, Donald McLaren
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D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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On Wed, Jun 24, 2015 at 5:16 PM, Ned <[log in to unmask]> wrote:

Hello All

When I run basic model t test, I selected both gray, white and csf segmented files for one group and similarly for other group and ran t/F test. Unfortunately I did not get any results or no voxel at any significance level.

However, when I do that separately, like doing only gray matter images between con vs KO mouse groups, it came out with significance voxels.

 

My question is do I have to do T/F test three different tissues separately to get results?

 

If so, how do I put together all significant voxels for three different tissues in a single template?

 

Is there anything am I doing wrong?

Thanks in advance

 

Ned

Assistant Scientist

BIRC

University of Georgia

Athens, GA -30019