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Dear all, I have fitted atomic coordinates of complete ribosome into a 5.5 Ang cryo map using "Fit in map" tool in Chimera. Now, at many positions the pdb seems to be not fitting and completely out of density. I would like to know if we have any software/server which could read a pdb/mmcif structure so big as ribosome and refine it according to the map. It looks like Refmac could be used to do it but I guess it only wants the input in .mtz format and I could not find a tool for converting .mrc to .mtz. Any help will be highly appreciated. Best Tofayel