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SPORTS MEDICINE :

MEDICAL: CONDITIONS: CONCUSSIONS :

MEDICAL: RESEARCH:

Johns Hopkins Study of Retired NFL Players
Sheds Light on Concussion-Related Brain Damage

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Johns Hopkins Study of Retired NFL Players
Sheds Light on Concussion-Related Brain Damage

Research provides further evidence of potential long-term neurological 
risks to football players who sustain repeated head injuries

Marin Hedin

January 26, 2015

Posted in Health, Science+Technology

Tagged concussions, head injuries

HUB

http://hub.jhu.edu/2015/01/26/nfl-players-concussion-research#

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A team of Johns Hopkins specialists has gathered evidence of accumulated 
brain damage in former NFL players that could be linked to specific memory 
deficits experienced decades after the men stopped playing the game.

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The small study, which involved imaging and cognitive tests of nine former 
NFL players, provides further evidence of the potential long-term 
neurological risks to football players who sustain repeated concussions. 
It also strengthens the argument of those calling for better player 
protections.

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Results of the study are published in the February 2015 issue of the 
journal Neurobiology of Disease.

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"We're hoping that our findings are going to further inform the game," 
says Jennifer Coughlin, assistant professor of psychiatry and behavioral 
sciences at the Johns Hopkins University School of Medicine. "That may 
mean individuals are able to make more educated decisions about whether 
they're susceptible to brain injury, advise how helmets are structured, or 
inform guidelines for the game to better protect players."

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Several anecdotal accounts and studies have suggested that athletes 
exposed to repeat concussionsincluding collegiate and professional 
football, hockey, and soccer playerscould suffer permanent brain damage 
and deficits from these events. However, the mechanism of damage and the 
source of these deficits have remained unclear.

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To understand them, Coughlin; Yuchuan Wang, assistant professor of 
radiology and radiological science at the JHU School of Medicine; and 
their colleagues used tests to directly detect deficits and to quantify 
localized molecular differences between the brains of former players and 
of healthy people who didn't play football.

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The complete article may be read at the URL above.

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Neuroinflammation and brain atrophy in former NFL players: An in vivo 
multimodal imaging pilot study

     Jennifer M. Coughlina, 1,
     Yuchuan Wangb, 1,
     Cynthia A. Munroa, e,
     Shuangchao Mac,
     Chen Yued,
     Shaojie Chend,
     Raag Airanb,
     Pearl K. Kima,
     Ashley V. Adamsa,
     Cinthya Garciaa,
     Cecilia Higgsa,
     Haris I. Sairb,
     Akira Sawaa,
     Gwenn Smitha,
     Constantine G. Lyketsosa,
     Brian Caffod,
     Michael Kassiouf, g,
     Tomas R. Guilarteh,
     Martin G. Pompera, b, ,


doi:10.1016/j.nbd.2014.10.019

Neurobiology of Disease

Volume 74, February 2015, Pages 5865


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