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Andy, the screenshot you attached verifies that something went wrong, but not at what point. As I said, go through every step in succession and check that afterwards, things are as they should be. As I also said, the most likely reason (at first glance) seems to be that the image(s) you derived the normalization parameters from and the image(s) you applied them to are not in register. Cheers, Marko Andy Yeung wrote: > Dear Marko and others, > > I re-performed everything again. > I don't know why overlay section wmsY* looks so atray, rotated and enlarged. > All other subjects were fine. > Could this screenshot help to answer what went wrong? > Thanks. > > Yours sincerely, > Andy > > > On Mon, Dec 16, 2013 at 4:24 PM, Marko Wilke > <[log in to unmask] > <mailto:[log in to unmask]>> wrote: > > Andy, > > the glass brain tells you that something went severely wrong, but > this should not be your only way to check for processing errors. > Look at the raw data, follow each step, and see where things go > astray. My bet would be that coregistration of functionals and > anatomicals did not work and you then applied the spatial > normalization parameters of the anatomical to not-in-register > functionals, but that is only a guess. > > Good luck, > Marko > > > Andy Yeung wrote: > > Dear all, > > I have finished data input for 13 subjects, all were fine. > But the 14th subject got the activation like this: outside the > glass brain. > I repeated standard procedures from realignment, coreg, segment, > normalize, smooth. > > Could anyone suggest what was going wrong? > Thanks a lot. > > Yours faithfully, > Andy > > > -- > ______________________________________________________ > PD Dr. med. Marko Wilke > Facharzt für Kinder- und Jugendmedizin > Leiter, Experimentelle Pädiatrische Neurobildgebung > Universitäts-Kinderklinik > Abt. III (Neuropädiatrie) > > > Marko Wilke, MD, PhD > Pediatrician > Head, Experimental Pediatric Neuroimaging > University Children's Hospital > Dept. III (Pediatric Neurology) > > > Hoppe-Seyler-Str. 1 > D - 72076 Tübingen, Germany > Tel. +49 7071 29-83416 <tel:%2B49%207071%2029-83416> > Fax +49 7071 29-5473 <tel:%2B49%207071%2029-5473> > [log in to unmask] > <mailto:[log in to unmask]> > > http://www.medizin.uni-__tuebingen.de/kinder/epn/ > <http://www.medizin.uni-tuebingen.de/kinder/epn/> > ______________________________________________________ > > -- ____________________________________________________ PD Dr. med. Marko Wilke Facharzt für Kinder- und Jugendmedizin Leiter, Experimentelle Pädiatrische Neurobildgebung Universitäts-Kinderklinik Abt. III (Neuropädiatrie) Marko Wilke, MD, PhD Pediatrician Head, Experimental Pediatric Neuroimaging University Children's Hospital Dept. III (Pediatric Neurology) Hoppe-Seyler-Str. 1 D - 72076 Tübingen, Germany Tel. +49 7071 29-83416 Fax +49 7071 29-5473 [log in to unmask] http://www.medizin.uni-tuebingen.de/kinder/epn/ ____________________________________________________