Dear Noki, Thanks very much for your helpful prompt. All the best. 2013-12-09 Rujing Zha 发件人:平林 直樹 <[log in to unmask]> 发送时间:2013-12-09 05:46 主题:Re: [SPM] gray matter density and volume obtained from vbm8 toolbox of SPM8 收件人:"SPM"<[log in to unmask]> 抄送: Dear Rujing, The wrp1- image is normalised image. m modulated m0 modulated non-linear only w warped r dartel warped p segmented 1 GM I recommend you read Structural Brain Mapping Group website(http://dbm.neuro.uni-jena.de/vbm/segmentation/, http://dbm.neuro.uni-jena.de/vbm/segmentation/modulation/) about the second question. All the best! Naoki --- On Thu, 2013/12/5, Rujing Zha <[log in to unmask]> wrote: Dear Naoki, Thanks very much for your precious reply. Here is my another two questions: 1, I saw the VBM8-Toolbox help and the m0* image is Modulated normalized, but I donot determine whether wrp1* is Normalised which didnot modulate. 2,The second quetion is principle of VBM. As I know, each voxel has a intensity value in GM volume. I want to know how intensity value in each voxel can represent GM density and volume in each voxel. Can you briefly explain it or just suggest a related paper or introduction about this? Thanks. All the best. 2013-12-05 Rujing Zha 发件人:平林 直樹<[log in to unmask]> 发送时间:2013-12-05 15:36 主题:Re: [SPM] gray matter density and volume obtained from vbm8 toolbox of SPM8 收件人:"SPM"<[log in to unmask]> 抄送: Dear Rujing, You can get the GM density by "Normalized" images. You can get the GM volume by "Modulated normalized" images. Best wishes! Naoki Hirabayashi --- On Wed, 2013/12/4, Rujing Zha <[log in to unmask]> wrote: Dear all, I read the vbm8-toolbox manual, and I found a option "Modulated normalized - non linear only". If I select this option, I will get a relative region GM volume, which is corrected for individual brain size. I want to know how I can get the GM density in VBM8 toolbox of SPM8. Thanks. All the best. 2013-12-04 Rujing Zha