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I assume that you mean the individual subjects' results differ from the overall group results. This shouldn't be surprising, particularly if your patient group is very different from the control group.
However, I think the contrast you want to specify at the 2nd level is [1 -1], which will show you areas where con_0001 is larger in group 1 than in group 2.
On 12/07/2013 10:41 AM, Z G wrote:
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hi,
I have 2 group of fMRI data (patient & control) in a block design tasks(sensory motor) .
I run specify 1st level for all my image ,separately.(define t-contrast with name:active>rest & value:1).
then run specify 2nd  level /2sample t-test for my 2 groups.(define new contrast with value:1)
 
Then , I became confused *:-/ confused,when used whole brain Button and saw the activated regions map .
 
 activated regions map  in 1st and 2nd was defferent.
Is it comman???
I need to ROIs that are active in my tasks,but I dont know which is correct.
please help me.
I haven't enough time *:-S worried