Will we be able to get a map from this?

Crystal

From: Stephen Smith <[log in to unmask]>
Reply-To: FSL - FMRIB's Software Library <[log in to unmask]>
Date: Tuesday, April 9, 2013 10:24 AM
To: "[log in to unmask]" <[log in to unmask]>
Subject: Re: [FSL] FDG PET with Melodic

Hi
In this case the ICA "time series" are the subject weights - so (e.g.) read melodic_mix into Matlab, identify the column number that matches the spatial map component number that you "like" - and then do a statistical test between different timepoints (subjects) in that column of weights.
Steve.



On 9 Apr 2013, at 16:13, "Franklin, Crystal G" <[log in to unmask]> wrote:

Thank you for your quick response.  

So I have concatenated all my single subject images into a 4D NIFTI image and ran them through Melodic using single-session.  Now I have my components, but I am stuck on how to get my group  differences.  Any suggestions?

Thank you,
Crystal

From: Stephen Smith <[log in to unmask]>
Reply-To: FSL - FMRIB's Software Library <[log in to unmask]>
Date: Tuesday, April 9, 2013 9:21 AM
To: "[log in to unmask]" <[log in to unmask]>
Subject: Re: [FSL] FDG PET with Melodic

Hi - yes this should be possible.  If you have "time series" data for each subject then you should use group-ICA and dual-regression; if you only have a single summary image per subject then you should concatenate all images into a 4D NIFTI image and run "single-session" (default) melodic.

Steve.


On 9 Apr 2013, at 14:22, "Franklin, Crystal G" <[log in to unmask]> wrote:

Dear FSL,

I have a FDG PET study that contains 79 subjects that are either FH+ or FH-.  The data has already been preprocessed and registered into standard space.  I am now wanting to do an ICA analysis to get the components and then do group comparisons with these components.  Is this possible and if so, how do I go about setting this analysis up. 

Thank you,
Crystal


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Stephen M. Smith, Professor of Biomedical Engineering
Associate Director,  Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
+44 (0) 1865 222726  (fax 222717)
[log in to unmask]    http://www.fmrib.ox.ac.uk/~steve
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---------------------------------------------------------------------------
Stephen M. Smith, Professor of Biomedical Engineering
Associate Director,  Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
+44 (0) 1865 222726  (fax 222717)
[log in to unmask]    http://www.fmrib.ox.ac.uk/~steve
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