Postdoctoral Fellowship in Structural Biology: Bacterial tyrosine kinases and signalisation networks.

A post-doctoral position is available for highly motivated candidates to join the research group of Prof. Sylvie Nessler at University Paris-sud 11. We are concerned by the increase in drug-resistant bacteria and the need for new antibiotics. Our research focuses on the characterization of atypical bacterial protein kinases considered as potential therapeutic targets. The post-doctoral project consists in the resolution of the crystal structure of cytoplasmic tyrosine kinases in complex with their cognate protein substrates and activators.

Applicants should hold a PhD degree and have significant experience in protein production and X-ray crystallography. Additional background in molecular cloning is considered as a plus but not essential.

As one of the major research universities in France, University Paris-sod 11 houses well-equipped crystallization facilities. The synchrotron Soleil is located at only 5 km from the laboratory and Paris centre is at 30 min by train. Such an environment allows one to have a good balance of life and science.

The expected starting date is September 2012. Interested applicants should send a curriculum vitae, a summary of past research experience and accomplishments, and contact information of two or three references to [log in to unmask]