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My friendly GP nurse has told me I have 10YRCARD = 30% i.e. a 30% risk of developing cardiovascular disease over the next 10 years. I have been recommended statins for life, which will bring the 30% down to 23%. Can anybody point me please to the equations that will have been used to get these figures? (Risk-factors used seem to be age, smoking, alcohol, cholesterol, family history, weight, blood pressure and glucose intolerance.) Also, can anyone refer me to advice on side-effects of statins (if possible with statistics)? Thanks JOHN BIBBY PS: The above points are practical. The following is pedagogic: Kind friend says "10-year risk of 30% means that you probably won't get anything for 33.333333 years by which time you'll be a dead duck anyhow, so why worry?" Discuss. You may leave the list at any time by sending the command SIGNOFF allstat to [log in to unmask], leaving the subject line blank.