This is an interesting question which has come up at least once on the list previously. This is my argument: The t statistic is not a consistent estimator of an effect size. That is, for df -> Inf (for increasing sample size), var(t) -> 1. This is because t gradually approximates z, the normal variate, at infinite degrees of freedom. Instead, let b_hat a parameter estimate in a linear model (the values in con images), and then we have for df -> Inf, var(b_hat) -> 0. That means b_hat is a consistent estimate of b, as it implies Prob([b_hat - b] > epsilon) -> 0. (Actually, it's well known that parameter estimates in a linear model are consistent, so my argument only concerns t.) > > Why in the second level of analysis in SPM the con images are used > but not spmT images? I am a biologist and not an expert in > statistics, thus I need a simplified explanation, if possible. > > Thank you in advance for your responses! > > Sincerely yours, > Vladimir >