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Dear all
I am sending this email again since I've had no responses and am
pleading for some assistance




I have had an enquiry in response to a reviewer's comment on the
description of the power and sample size for a single cohort study
methodology (ie there is no comparator or 'unexposed' group; all a
priori comparisons are made internally between subgroups). We use the
sample size tables from Machin for estimates of suitable sample size
when background is unknown (as is generally the case for unexpected
adverse events)

 

Specifically they query '...whether one can actually use the term
'power' in such 'exposed-only cohorts....'  And also ' how do you
calculate a p-value in an exposed-only cohort study'.....

 

I'm really not sure what the point the reviewer is trying to make? Can
anyone interpret their enquiry into something meaningful?

Your hopefully

Debbie

A Non-statistician

 

 




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Please Note

This email is private and intended for the addressee(s) only. It may contain information that is proprietary. Any dissemination, distribution or copying of information contained is unauthorised and prohibited if you are not the recipient. If you have received this message in error, please delete/destroy it.

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