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Thanks for your answer.

In fact, I have tried to do the analysis on 3 subjects in order to understand how it works. I have used this line command:
concat_bvars L_Hipp_all.bvars con*_L_Hipp_first.bvars dis*_L_Hipp_first.bvars
I have modified it to adapt it to my sample:
concat_bvars L_Hipp_all.bvars *_L_Hipp_first.bvars
A L_Hipp_all.bvars has been created but I'm not sure the concatenation worked.
How can I be sure of that?

Then I have used my design with 2 EVS: group and age
EV group      EV age demean
1                0.8
1                -0.2
1                0.3

and I use 
first_utils --vertexAnalysis --usebvars -i L_Hipp_all.bvars -d L_Hipp.mat -o
shape_analysis/L_Hipp --useReconNative --useRigidAlign -v
>& shape_analysis/L_Hipp.txt
I have a error message which says: 
cannot open the file
Can't find the L_Hipp.txt

Could you tell me the line commands I have to use in order to work on my group? Those available on the FSL MRI ara adapted to comparison group! Can you tell me those who are adapted to study only ONE group?

Thanks
Charlotte


> Date: Mon, 31 Jan 2011 16:49:58 +0000
> From: [log in to unmask]
> Subject: Re: [FSL] Problem with FIRST vertex analysis
> To: [log in to unmask]
> 
> Hi,
> 
> That is a lot of subjects.
> How much memory (RAM) is available on your machine?
> 
> I would recommend that you try a subset of the data initially
> to see if you have everything correct (try with 30 subjects).
> If that works then try increasingly larger sets until you run
> into the problem.  At that point we should be able to figure 
> out if it is a memory problem and if so, how much you need.
> 
> Also, I don't know what your "modifications" are - do you just
> mean a different design matrix?
> 
> All the best,
> 	Mark
> 
> 
> On 31 Jan 2011, at 11:20, SUBSCRIBE FSL Anonymous wrote:
> 
> > Dear FSL users,
> > 
> > I would like to perform a vertex analysis with FIRST. I have 331 subjects. I would to study a correlation between cognitive  performances and hippocampal volumes. I have tried to concatenate my bvars file. Anex file is created but I believe it doesn't work. In the secund step of the analysis, I can read a error meaage: cannot open the file... 
> > I apply the command line with modifications because I only have one group. 
> > Can somebody help me?
> > 
> > Thanks
> > Charlotte
> >