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Here is an good example for ROI time series data correlation in RS-fMRI: "Mapping the functional connectivity of anterior cingulate cortex" by Daniel S. Marguliesa, A.M. Clare Kellya, Lucina Q. Uddina, Bharat B. Biswalb, F. Xavier Castellanosa, c, , and Michael P. Milham NeuroImage Volume 37, Issue 2, 15 August 2007, Pages 579-588 On Thu, Aug 13, 2009 at 12:19 AM, Tal Herbsman<[log in to unmask]> wrote: > Dear FSL users, I would appreciate some advice on this: I am interested in doing > correlation analysis on time series data extracted w/ fslmeants of various anatomical > ROIs from FEAT preprocessed fMRI data. I have a set of nuisance time series (CSF, WM > and whole brain global drifts). What would be the correct way of regressing these > nuisance covariates out of my time series? I can think of two ways but am not sure which > (if any) is correct, nor how to implement them: > > 1. orthogonalize the ROI time series with respect to global drift time series. Is the FSL > orthogonalization available as a separate command line program? > > 2. use GLM to figure out PEs for nuisance regressors and subtract from signal. Not sure > how to go about doing this. > > Any ideas? > > Tal. > > > Tal Herbsman, MD > > Assistant Professor > Department of Psychiatry > University of Wisconsin School of Medicine and Public Health > 6001 Research Park Blvd. > Madison, WI 53719-1176 > > Office: (608) 263-6100 > Fax: (608) 263-0265 > [log in to unmask] > > -- Best Regards National Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal University Beijing, China. 100875 Tel: +86-13810154455 web: http://psychbrain.bnu.edu.cn ============================================== Welcome to MuDuo JinSheng BBS @ Beijing Normal University telnet://bbs.mdjs.org http://bbs.mdjs.org