Dear all,
this is a question to all you registration gurus.
For coregistration between different MRI modalities for the same
individual (eg registering for exampe an EPI image to a T1 weighted
structural), most of us routinely use rigid body coregistration. For
normalization to some template space, many non-rigid normalization
algorithms are available.
As for between modality coregistration works reasonably well for lower
field strenghts and/or fast EPIs, it would also be handy to allow some
non-lineairity, similar as in normalization, possibly also taking into
account spatial biases (for example due to parallel imaging), and
probably other effects.
For example, EPI images are always more or less spatially distorted as
compared to a T1 weighted structural image, yielding a poor match when
using rigid-body registration. Especially at higher field strengths (7T)
this is real issue, or for high resolution fMRI (<3 mm^3). Non-rigid
coregistration would be quite handy in such cases, for example modeling
spatial distortions using DCT spatial basis functions, like in
normalization.
Are there toolboxes availbale to do non-rigid coregistration for
matlab/spm, or are some of you willing to share some home brew code or
experiences?
Thanks in advance,
Bas
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Dr. S.F.W. Neggers
Division of Brain Research
Rudolf Magnus Institute for Neuroscience
Utrecht University Medical Center
Visiting : Heidelberglaan 100, 3584 CX Utrecht
Room B.01.1.03
Mail : Huispost B.01.206, P.O. Box 85500
3508 GA Utrecht, the Netherlands
Tel : +31 (0)88 7559609
Fax : +31 (0)88 7555443
E-mail : [log in to unmask]
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