Armin, This dummy.m script below should help. For example, if you have 200 scans, and scans 45, 47 and 48 were bad, this Xd = dummy(200,[45,47,48]); save Xd Xd.mat will create the 3 columns you need to add to your design matrix and save them in a mat file. Then, use the 'MultipleRegressors' option in the 1st level fMRI design specification to enter these as nuisance regressors. -Tom % Create dummy (indicator) variables % FORMAT [X] = dummy(n,I) % n - Number of scans/rows % I - vector of scans/rows to model %___________________________________________________________________________ % % Creates dummy vectors, suitable for entering as additional regressors % in a SPM analysis. % % If I has length p, then X is a n-by-p matrix of all zeros, except % column k has a one at the I(k)'s row. % %___________________________________________________________________________ % $Id: dummy.m,v 1.1 2005/08/18 21:01:11 nichols Exp $ p = length(I); X = zeros(n,p); for i = 1:p X(I(i),i) = 1; end return On Tue, Jul 29, 2008 at 9:16 AM, Armin Blickenstorfer < [log in to unmask]> wrote: > Dear Stephen, > > I'm fairly new to SPM and I'm interessted in a greater detail on how you > would > imply a new regressor. > > I hope I do not ask too much > > > Armin Blickenstorfer > PhD Student > > ____________________________________________ Thomas Nichols, PhD Director, Modelling & Genetics GlaxoSmithKline Clinical Imaging Centre Senior Research Fellow Oxford University FMRIB Centre