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Hi The only way at present (assuming that you mean some kind of standard system compression, e.g. gzip, bzip, compress, zip), would be to have a shell script which uncompresses the images on the fly. Of course, if you had images that were compressed according to the PCK format (or similar), or used one of the img-CIF compression methods, it would be done automatically by Mosflm. Dear All, I was wondering if there is some king of trick that would allow to use a compressed diffraction image during data processing. Best wishes, Andrzej Lyskowski HelveticaHarry -- Dr Harry Powell, MRC Laboratory of Molecular Biology, MRC Centre, Hills Road, Cambridge, CB2 2QH