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I've seen Maillard/Amadori products of proteins before, but not exactly what you're describing. The glycoside of arginine should not be stable. Could you post an electron density snapshot? Artem -----Original Message----- From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of Michael Colaneri Sent: Wednesday, May 23, 2007 8:00 PM To: [log in to unmask] Subject: [ccp4bb] can glucose covalently bond to the guanidino nitrogen of arginine? Dear colleagues, Has anyone seen a glucose covalently bonded to the guanidino nitrogens of Arginine via a glycosidic bond? Thanks. Mike Colaneri