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Hi Film calculates voxel-wise pre-whitening matrices Woolrich, M, Ripley, B., Brady, J and Smith, S. (2001) Temporal autocorrelation in univariate linear modelling of FMRI data. NeuroImage, 14(6):1370-1386. The technical report TR01MW1 is available at http://www.fmrib.ox.ac.uk/analysis/techrep/ cheers christian On 10 Dec 2004, at 22:23, Mark Elliott wrote: > Can someone please point me to a detailed description of how FSL > implements its prewhitening (FILM) step. In particular, is a global > estimate of AR(1) derived and then applied similarly to all voxels? > i.e. > one pre-whitened design matrix for all voxels. > > Thanks. > > -- Christian F. Beckmann Oxford University Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK Email: [log in to unmask] - http://www.fmrib.ox.ac.uk/~beckmann/ Phone: +44(0)1865 222782 Fax: +44(0)1865 222717