Dear Serge, > I am trying to do a second level analysis with repeated measures per > subject. The simplified version is: > a group of 10 subjects, consisting of two subgroups of 5 subjects each, and > 2 copes per subject (in reality I have 3 groups, 87 subjects and 7 copes). > > Copes were generated using a model with orthogonal regressors at first > level. > I want to apply an analysis with 2 repetitions per subjects (the two copes) > and test whether cope1 distinguishes the two subgroups of 5 subjects better > than cope 2. > My design then is as follows: > group EV1 EV2 EV3 > EV4 ... EV12 > subject 1, cope 1 1 1 0 1 > 0 0 > subject 1, cope 2 1 0 1 1 > 0 0 > subject 2, cope 1 1 1 0 0 > 1 0 > subject 2, cope 2 1 0 1 0 > 1 0 > > ...... > > subject 9, cope 1 1 -1 0 0 > 0 0 > subject 9, cope 2 1 0 -1 0 > 0 0 > subject 10, cope 1 1 -1 0 0 > 0 1 > subjects 10, cope 2 1 0 -1 0 > 0 1 > Contrasts: > 1 0 0 0 0 0 0 0 0 0 0 0 : first 5 subjects > last 5 subjects for cope 1 > > 0 1 0 0 0 0 0 0 0 0 0 0 : the same for cope 2 > > 1 -1 0 0 0 0 0 0 0 0 0 0: is the difference between the two subgroups > greater for cope 1 than for cope 2? > > etcetera I cannot see why you have included EVs for subject means (EVs 3-12). You should replace them with EVs for the cope means: group EV1 EV2 EV3 EV4 subject 1, cope 1 1 1 0 1 0 subject 1, cope 2 1 0 1 0 1 subject 2, cope 1 1 1 0 1 0 subject 2, cope 2 1 0 1 0 1 ...... subject 9, cope 1 1 -1 0 1 0 subject 9, cope 2 1 0 -1 0 1 subject 10, cope 1 1 -1 0 1 0 subjects 10, cope 2 1 0 -1 0 1 then a [1 -1 0 0] contrast should give you what I think you are after. > So far I am happy with my design. But I need to include one covariate for > age and one for gender as well. The demeaned age EV (EV13) would be > something like: > 12 > 12 > -7 > -7 > ... > -11 > -11 > 6 > 6 Yes, you can simply put this in as an extra EV. > To avoid rank deficiency, I can remove EV12 (the EV of subject 10), but I am > not sure whether this is allowed. with EVs3-12 removed this shouldn't be a problem. Best Regards, Mark Woolrich.