Thomas and Lundeberg (who else?) compared the effects of acupuncture and
diazepam (as well as placeboes of each) on both affective and sensory
components of pain. Affective pain was effected more strongly.

Panos, I agree exactly. A recent study in Germany was unable to confirm the
findings of Cho et al. Still being analysed to see if they match those of
Wu - the science is still immature adn errors are easy.


Thomas M, Eriksson SV, Lundeberg T. A comparative study of diazepam and
acupuncture in patients with osteoarthritis. Am J Chin Med 1991;19:95-100.

At 09:49 22/06/01 +0100, you wrote:
>this is getting very interesting. It is perplexing that a paper by Wu et al
>(1999, Radiology,212. 133-141) has not attracted as much attention as the Cho
>paper. In that paper the authors demonstrate that areas in the brain are
>down' whilst others 'light up' during stimulation. the interesting thing
is that
>the ones that 'shut down' are areas associated with emotion, whilst the ones
>that show increased activity are those which are traditionally thought to
>modulate pain. Hence, one can (very cautiously) assume that stimulation with
>acupuncture will have some degree of central modulation of emotion as well
as an
>analgesic effect. The trick now is, to find out how best to stimulate such
>we can achieve both of these effects maximally. In some way, it may even
>the A and B paradigms that Lynn is quoting below, if we assume that one
type of
>stimulation achieves emotional (but not nociceptive) modulation and vice
>Keep the comments coming!
>Take care
>Anthony Campbell wrote:
>> On 20 Jun 2001, lppc wrote:
>> > Panos has responded regarding the autonomic nervous system and
>> > acupuncture's effect on it.
>> > This takes me into the realms of pain and emotion, and I wondered if
>> > anyone had any thoughts on the following:
>> >
>> > 'pain is an unpleasant sensory and/ or emotional experience'
>> >
>> > If acupuncture is modulating pain/emotion through similar neural
>> > pathways, what do people feel is happening in the patient who says;
>> >
>> > A       'my pain is no better, but I feel better'
>> > or B    ' my pain is better but I still feel the same'
>> >
>> > Professor Cho, in his recent book ' Neuro-Acupuncture' makes this
>> > statement, ( which might add more info. to the Blood pressure debate...)
>> >
>> > ' Acupuncture goes beyond the simple pain control mechanism. It includes
>> > more homeostatic and controlling functions such as the balance of the
>> > humoral and autonomic functions, and the control of neurochemicals. This
>> > involves co-operation between the major monoaminergic and endorphinergic
>> > neuronal sites in the brainstem and lower brain'
>> >
>> > So, I'm asking people to give me their thoughts on how you can use
>> > ' acupuncture for pain'  , when maybe you can't 'scientifically'
>> > distinguish between the pain and emotion effect... back to the patient
>> > examples A and B!...
>> >
>> > Thoughts??
>> >
>> >
>> > Lynn
>> > --
>> > lppc
>> >
>> >
>> This is something I have also thought about in relation to acupuncture.
>> When prefrontal leucotomies were in vogue patients often said that after
>> the operation they continued to feel pain but it no longer bothered
>> them. For a detailed discussion of the relation between emotion and
>> thought, see Antonio Damasio, "Descartes' Error: Emotion, reason and the
>> human brain".
>> Another clue comes from experiments in which angina was experimentally
>> induced in patients with dobutamine infusion while PET scans were
>> carried out on their brains. Changes were seen in the posterior thalamus
>> and frontal cortex. When the pain disappeared, activity persisted in the
>> thalamus but ceased in the cortex. These effects are not seen in somatic
>> pain; the patterns in somatic and visceral pain are different. The
>> researchers suggest that these findings may explain silent myocardial
>> ischaemia. It occurs to me that they could also be relevant to
>> acupuncture analgesia for visceral pain; it should be easy to
>> investigate for anyone with access to PET scanning.
>> (ref: Rosen SD et al., Central nervous pathways mediating anginal
>> pectoris. Lancet 1994;344:147-150.)
>> Another possible example of functional disconnection within the central
>> nervous system arises from the finding that some patients laugh when
>> receiving acupuncture. In the disorder called pain asymbolia, patients
>> feel pain but don't experience the emotional accompaniment; also, they
>> giggle when pricked. The disorder is supposed to be due to disconnection
>> between the insular cortex and anterior cingulate. We know that
>> acupuncture has considerable effects on the limbic system generally and
>> the anterior cingulate in particular, and it seems possible that
>> patients who continue to feel pain but are less bothered by it are
>> experiencing a degree of functional disconnection between the insular
>> cortex and anterior cingulate.
>> (See my paper, The Limbic System and Emotion in Relation to Acupuncture,
>> available online at my website:
>> http://www.acampbell/org/acupuncture/articles/limbic.html.)
>> Anthony Campbell
>> --
>> Anthony Campbell - running Gnu/Debian Linux (Windows-free zone).
>> For electronic books (Homeomythology and The Assassins of Alamut),
>> essays, and over 130 book reviews, go to
>> Le style est l'homme meme. (Style is the man himself.)
>>                                               [Buffon]
>Attachment Converted: "c:\eudora\attach\p.barlas2.vcf"
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