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In message <[log in to unmask]>, Mike Hallworth
<[log in to unmask]> writes
>>We Had a similar query from a dermatologist: we told him to monitor FBC as
>this was more readily available >than assaying the drug itsef, monitored
>the drugs effect AND was significantly cheaper!
>
>This is missing the point! The advantage of TPMT measurement is that you
>can detect susceptibility to azathioprine *before* you give it, and adjust
>the dose accordingly, rather than monitoring FBC afterwards to see how much
>damage you've done...
>
>Mike Hallworth

But what is the sensitivity and diagnostic efficiemcy (cost is unimporatnt of
course - but there are a lot of folk on azothiaprine)

-- 
paul collinson


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