Dear list members
I am trying to validate or refute a claim that in the large Physicians'
Health Study of 20000 US doctors, which included a RCT of aspirin vs placebo
in prevention of cardiovascular outcomes, 75 percent of the control group
chose to take aspirin anyway. I started hunting this as an example of a
study to illustrate the pitfalls in intention-to-treat analysis. I can't
find any reference to the behaviour of the control group anywhere, but it's
not a literature I'm familiar with. Can anyone help? Please reply to me
direct and I'll collate for the list to avoid excess postings.
thanks
trish
Dr Trish Greenhalgh
Senior lecturer in primary health care
Unit for Evidence-Based Practice and Policy
Royal Free & University College Medical School
Department of Primary Care & Population Sciences
Archway Resource Centre
2nd Floor, Holborn Union Building
Highgate Hill, London N19 5NF
Personal Assistant and Unit Administrator (Marcia Rigby): + 44 (0) 171 288 3246
Fax: + 44 (0) 171 281 8004
email [log in to unmask]
Websites
Unit for Evidence Based Practice:
http://www.ucl.ac.uk/primcare-popsci/uebpp/uebpp.htm
MSc in primary care: http://www.ucl.ac.uk/primcare-popsci/msc/index.html
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