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ALLSTAT  1999

ALLSTAT 1999

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Subject:

Seminar on Down's syndrome screening, London

From:

"Alan K. Hackshaw (EPM) 136283" <[log in to unmask]>

Reply-To:

Alan K. Hackshaw (EPM) 136283

Date:

Thu, 7 Oct 1999 14:33:20 GMT

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (37 lines)

The next Wolfson Institute seminar will be held on Tuesday 12 October 
1999 at 4pm.

Title: A new approach to antenatal screening for Down's syndrome
        (Recently reported in the New England Journal of Medicine)

By: Professor Nicholas Wald
St Bartholomew's & The Royal London School of Medicine & Dentistry

Screening for Down's syndrome in pregnancy is now widespread . 
The most commonly used method is a blood test at 15-22 weeks of 
pregnancy. The test identifies 5% of women with the highest risk and 
then offers them an invasive (and possibly harmful) diagnostic test to confirm 
whether the fetus has Down's syndrome or not; this method can detect about 70% of
affected pregnancies. Recently, screening is performed in some places earlier in
 pregnancy (10-14 weeks) using a blood test and ultrasound, again by offering 
invasive testing to the 5% of women with the highest risk. A new approach to
 screening is to combine first and second trimester information into a single test. 
This approach can identify 85% of affected fetuses by only offering 
an invasive test to 1% of women, representing a significant improvement in 
 efficacy and safety compared to existing screening methods. 
This new approach will be described and discussed.

The seminar will be held at:
The Wolfson Institute of Preventive Medicine
St Bartholomew's & The Royal London School of Medicine
Charterhouse Square
London EC1M 6BQ.

Nearest underground stations: Barbican and Farringdon

Please contact Dallas Allen on 0171 982 6281 for details.



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