COURSE: Introduction to Trials within Cohorts (TwiCs)
DATE: 9 September 2019
VENUE: Pragmatic Clinical Trials Unit, Whitechapel Campus, Queen Mary, University of London
We would like to inform you about an upcoming course, Introduction to Trials within Cohorts (TwiCs), taking place at the PCTU on Monday 9th September 2019.
TwiCs studies collect data on the exposures and outcomes of a group of patients (i.e. cohort). This provides a platform for research, including multiple randomised trials with usual care comparators. Those joining the cohort initially grant permission for their data to be used for intervention research. For each succeeding randomised trial, a proportion of those eligible are randomly selected to be offered the intervention, and their outcomes compared to those eligible patients not offered the intervention (these may be new interventions or interventions already being routinely delivered). Patients randomised to this offer group are told (after randomisation) that they have been randomly selected, and a secondary consent, clinical in character, is obtained to receive the intervention. In most studies using the TwiCs approach, cohort patients explicitly consent to not know at a future date if they have been randomised to usual care. Please find the flyer attached.
For further details about the course and to book your place, please visit the event page on our website:
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