Dear all,
A two-day course on Mendelian randomization will take place in Cambridge at the MRC Biostatistics Unit in Cambridge on Monday 19th November and Tuesday 20th November 2018 run by Stephen Burgess (Cambridge), Verena Zuber (Imperial), Robert Scott (GSK), Chris Foley (Cambridge) and Jessica Rees (Cambridge).
Overview: Studies based on Mendelian randomization are increasingly being used to distinguish causal relationships from observational associations in epidemiology and to prioritize potential targets for pharmaceutical intervention. This course intends to explain both simple and more complex statistical methods for causal inference in Mendelian randomization studies, and the instrumental variable assumptions on which they are based. The course includes computing practicals (R and Stata will be supported).
Objectives: After the course, participants should have sufficient knowledge to undertake their own Mendelian randomization analyses, to understand the assumptions on which causal inferences are based, and to critically appraise published studies based on Mendelian randomization.
Intended audience: Quantitative epidemiologists and medical / applied / pharmaceutical statisticians. The course material is relevant to causal inference in both epidemiology and drug development, and would be particularly suitable for a PhD or post-doc about to start a project using Mendelian randomization.
Prerequisites: Knowledge of applied statistical methods used in epidemiological studies is assumed (e.g. epidemiological study designs, logistic regression). No prior knowledge of genetics, instrumental variable techniques, or Mendelian randomization is necessary.
Symposium: On the Wednesday morning, there will be a half-day symposium that is open to course participants (see separate email). It is not a formal part of the course, and it will also be open to non-course attendees. The aim of the symposium will be to present more cutting-edge methodology for Mendelian randomization that is either still under development, or not relevant to all applications of Mendelian randomization.
All refreshments and meals are included in the course fees. The book by Burgess and Thompson "Mendelian Randomization: methods for using genetic variants in causal estimation" (Chapman & Hall, 2015) will be provided as part of the course.
For more details: http://mendelianrandomization.com/index.php/course-details.
Registration: https://onlinesales.admin.cam.ac.uk/conferences-and-events/mrc-biostatistics-unit/mrc-biostatistics-unit-short-courses/mendelian-randomization-course-19-20-november-2018.
We hope to see you on the course in November.
With best wishes, Stephen Burgess
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