Hi Stef,
do you by any chance run your analysis or your SPM installation in a dropbox shared folder? I'm afraid this might not be a good idea, as dropbox file synchronisation may interfere with MATLAB and SPM file locking, possibly causing various issues. You should keep all software and data local or on a LAN share directly supported by your OS (or at least switch off dropbox synchronisation while you are working in the shared folder).
Hope this helps
Volkmar
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