A position for a PhD Student in Computational Biochemistry is available
in the group of Dr. Christo Z. Christov in the Department of Chemistry
at Michigan Technological University, Houghton, MI.
The research project will be focused on understanding enzyme reaction
mechanisms, dynamics and ligand binding in reference to experimental
structural, spectroscopic and biochemical studies.
The project will involve learning and applying of Multilevel Molecular
Modeling Methods such as Combined Quantum Mechanical and Molecular
Mechanics (QM/MM) methods, Molecular Dynamics (MD) studies,
Electronic Structure Methods and Free Energy Calculations. The main
focus of the studies will be on transition metal-containing enzymes
involved in epigenetic regulation (histone- and DNA-demethylases)
but also on other enzymes (e.g. matrix metalloproteinases) and proteins
(e.g, membrane transporters). The research will likely involve intensive
collaborations with other research groups at Michigan Tech,
other USA and EU Universities and pharmaceutical companies.
The individual interests and background skills of the students will be
taken into account in designing the research studies. The ideal
applicants should demonstrate the following qualifications, experience
and interests:
BSc in Chemistry, Biochemistry or similar discipline
Some background and/or strong motivation for research in
computational chemistry, biomolecular modeling and drug design
with focus on enzyme mechanisms and dynamics
Some experience and/or strong interest for computational
work, Linux, shell scripting
The position is funded by the Department of Chemistry through
allocations from the Graduate School as Graduate Teaching
Assistants for up to 5 years with satisfactory progress to degree.
Teaching undergraduate students is expected. The applicants
should have at least a BSc degree in Chemistry, Biochemistry or
similar discipline.
The start date should be no later than August 2018. For a
preliminary assessment, interested applicants should contact Dr.
Christov by e-mail at christov|-|mtu.edu along with a current CV
and a brief description of research interests and experience.
For official consideration, all applications for admittance into the graduate school must be submitted through the university's online
process. More details about the application procedures can be found at:
http://www.mtu.edu/chemistry/graduate/program/.
EEO/AA Policy: Michigan Technological University is an Equal
Opportunity Educational Institution/ Equal Opportunity Employer,
which includes providing equal opportunity for protected veterans and
individuals with disabilities.
To join or leave the molecular-dynamics-news email list, go to:
http://www.jiscmail.ac.uk/lists/molecular-dynamics-news.html
|