Hi,
Three subjects is certainly too small for reliable statistics. However, you can qualitatively describe this in a medical case report or similar. If you want to do statistics then we would normally recommend minimum numbers of around 12 to 15.
All the best,
Mark
> On 6 Jan 2018, at 14:18, Josue Avecillas <[log in to unmask]> wrote:
>
> Dear Experts,
>
> I have a group of 3 patients with some side effects related with surgical intervention. I wanted to combine the whole-brain probabilistic tractograms of these three subjects to describe what connections they have in common. However, I don't know if this make sense in terms of the number of subjects.
>
> Is there a specific n of subjects to consider meaningful the group probabilistic maps?
>
> Thank you!
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