yes, I would believe that the reviewer is correct. If you search the
list archives for "AC-PC", "manual reorientation" or "coregistration
with template" then you will find many threads detailing how this is
usually done, and why it is recommended.
> I work in an experimental form of neuroimaging that, for this study,
> only produces 30mm slabs of central brain. Given that context, I think
> the SPM normalization works awfully well, but not every time. Now the
> paper is in revision and a reviewer writes:
> "The normalization failure rate is high, which is noted by the authors.
> At least some of the failures may be corrected by manually adjusting the
> position of the data (in the image header) so that it starts from a
> position that is already close to that of the MNI template."
> Is this true? I believe SPM starts with an affine transform, would this
> be improved by a previous manual rigid-body transformation?
> Eric Barnhill PhD
> Charité Universitätsmedizin Berlin
> Sent from ProtonMail <https://protonmail.ch>, encrypted email based in
Prof. Dr. med. Marko Wilke
Facharzt für Kinder- und Jugendmedizin
Leiter, Experimentelle Pädiatrische Neurobildgebung
Oberarzt der Abteilung Neuropädiatrie
Marko Wilke, MD, PhD
Head, Experimental Pediatric Neuroimaging
Consultant in Pediatric Neurology
University Children's Hospital
D - 72076 Tübingen, Germany
Tel. +49 7071 29-83416
Fax +49 7071 29-5473
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