Dear All,
I’m doing VBM analysis on alzheimer patients using SPM and CAT.
I followed the guidelines on CAT12 manual to create a customized DARTEL template, but i’m using only a subsample of all my data (as done in some previous studies like Spreng & Turner, 2013, but they are not using CAT).
According to the manual, when you normalize to MNI defining a Gaussian FWHM you don’t have to smooth subsequently if you run the statistical analysis on the same images used to create the DARTEL template.
In my case however i will use the normalized template to resegment the original T1, so i should smooth the final segmentation before running statistical analysis. Am i correct?
What do you think?
Thank you.
Best,
Giuliano
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