Dear FSL experts,
I would like to perform structural covariance analysis (AKA source-based morphometry: SBM) using Melodic, as described in the following papers:
Hafkemeijer A, Altmann-Schneider I, de Craen AJM, Slagboom PE, van der Grond J, Rombouts SARB (2014): Associations between age and gray matter volume in anatomical brain networks in middle-aged to older adults. Aging Cell 13:1068–1074.
Coppen EM, van der Grond J, Hafkemeijer A, Rombouts SARB, Roos RA. (2016): Early grey matter changes in structural covariance networks in Huntington’s disease. NeuroImage: Clinical 12:806–814.
Hafkemeijer A, Möller C, Dopper EGP, Jiskoot LC, van den Berg-Huysmans AA, van Swieten JC, van der Flier WM, Vrenken H, Pijnenburg YAL, Barkhof F, Scheltens P, van der Grond J, Rombouts SARB (2016): Differences in structural covariance brain networks between behavioral variant frontotemporal dementia and Alzheimer’s disease: Structural Covariance in FTD and AD. Human Brain Mapping 37:978–988.
After running Melodic, I have two matrix files: melodic_mix and melodic_unmix. Which is the file containing each subject's loading for each structural networks and should be used for statistical analysis?
Thanks in advance,