Hello, I am sorry if this is a simple question for you, but I need help about vertex analysis.
I have never used this kind of analysis, therefore, I am afraid to make some error during the analysis.
Well... I have created all 4D files related to the different subcortical locations, together their masks.
I run RANDOMISE. For this project, I have also used a DTI analysis, therefore, I used the same design matrix that I used for the DTI analysis.
I have two groups: A - Patients; B - Healthy controls. Moreover, I used AGE and EDUCATION as covariates.
My design.mat is like this:
(group A - Group B - age - education)
/NumWaves 4
/NumPoints 72
/Matrix
1 0 54 6
1 0 36 6
1 0 39 6
1 0 32 6
...
0 1 42 4
0 1 22 4
0 1 26 4
0 1 21 5
0 1 22 6
...
while, my design.com is:
/NumWaves 4
/NumContrasts 2
/Matrix
-1 1 0 0
1 -1 0 0
Are they correct for the vertex analysis?
Do I also need the fts matrix?
I run RANDOMISE in this way:
randomise -i ALL_SUBJ_L_Accu_first.nii.gz -m ALL_SUBJ_L_Accu_first_mask.nii.gz -o ttest_L_Accu_first-d design.mat -t design.con -T -n 5000
Is it correct?
Moreover, I found a significant result (p<0.05), but when I retrieved the values for all subjects, I found that some subjects have positive values, others negative. Is it correct?
Thank you so much.
Miky
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