Thanks Donald.
I need to regress out the fitted response from ROIs time series (as described in Fair et al., 2007*) and check if the functional connectivity of specific ROIs (after regressing task-based response as confounding factor) is similar to their functional connectivity from continuous resting state data. Simply, I need to replicate Fair's study and emulate resting state from task-based data. In CONN, the "deionization step" can consider the task-based fitted responses as confounding factors and regress them out, so I was wondering if I can do the same in SPM using the multiple regression section in fMRI specification???
*Fair DA, Schlaggar BL, Cohen AL, Miezin FM, Dosenbach NUF, Wenger KK, et al. A method for using blocked and event-related fMRI data to study “resting state” functional connectivity. Neuroimage. 2007 Mar;35(1):396–405.
Maaly
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