Hello guys,
If I am not wrong, since the realease of the SPM5, some statistical analysis were excluded from the software, one of them was the Multi-Group: Conditions and Covariates. I would like to model a study using similar approach used by McNally 2005 in this ISAS paper. Is it possible to define a model like this in SPM12? How to procedure?
According Macknally, they used pairs of images for each group.
Description:
Now it is time to configure and estimate the statistical model.
Click PET from the model specification in the SPM menu window.
Select Multi-Group: Conditions and Covariates
Number of Groups: 2
Number of Subjects in Group 1: 1
Select the smooth-normalized-realigned (and/or masked) image scans (swr*.img) for your patient: SELECT THE INTERICTAL SCAN FIRST, THEN THE ICTAL SCAN .
NOTE: The Healthy Normals are added to the model with the Interictal scan followed by the Ictal. Selecting the Interictal scan (first) and then the Ictal, for the current patient is a key step for ISAS to work properly. Preserving this order allows for the conditions to be specified only once for the patient and Healthy Normals.
Condition:0 1 (space in-between, 0 = Interictal, 1 = Ictal)
Number of Subjects in Group 2: 99 (typing 99 indicates to the spm_spm_ui.m script that the Healthy Normals should be used).
Number of Covariates: 0
Number of Nuisance Variables: 0
Global Normalization: proportional scaling*
Prop Scan Global Mean: 50
Threshold Masking: relative
Analysis Threshold: 0.8
Global Calculation: mean voxel value**
Non-sphericity correction: no
Thank you
Henrique
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