On 01/07/16 14:26, Rafal Dolot wrote:
>
>
> I need advice with modeling DNA and RNA under Coot. I'm working with a
> heteroduplex model and I would simple switch chain DNA to RNA and RNA
> to DNA. Is it possible under this program?
Yes and no. The is no click-click button for it. You can, one by one
"Replace Residue" by the RNA equivalent.
Or you can hand edit the pdb file and change the residue names. Adding
the O2's is more tricky. I would add them in with dummy coordinates, fix
all the other RNA atoms and do a Regularize zone to zap the O2's into
ideal locations.
> In addition - there is only simple mutating tool for nucleic acids. Is
> there "Mutating and Auto Fit" option, like for proteins?
Sadly no.
Paul.
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