Hi Isaac,
Unless you're talking about a different question or set of findings, it's not clear to me that the approach employed by Leech would help you understand what's happening with VLPFC. Most reviewers won't have a problem with the fact that your VLPFC is not within the suprathreshold parts of DMN, assuming it fits in with your hypothesis or some theoretical framework.
Cheers,
David
> On Jun 29, 2016, at 11:30 PM, SUBSCRIBE FSL Isaac Unger <[log in to unmask]> wrote:
>
> Hi David,
>
> Firstly, thank you very much for those references. They are excellent!
>
> It is correct that my region “X” is not part of my network “Y”; the output of my dual regression is showing altered connectivity between a VLPFC region and the IC mapping the DMN.
>
> To run a seed/ROI approach as you have suggested, would you recommend a similar protocol to that used by Leech et al. (2012)?
>
> Thanks again,
> Isaac
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