Hi Barbara,
a few things you may want to check: one, there is a push and a pull
procedure to apply a deformation field, requiring the forward or the
inverse deformation field. Getting this wrong may lead to strange
results. Two, have you made sure that the T1 and the T2 are really in
register with each other? If they are not lining up nicely in native
space, then normalizing them with the parameters of one of them will not
work. A related issue is if you moved the T1 to line up with the T2
after you computed the spatial normalization parameters, in which case
the procedure you described will also not work.
Good luck :)
Marko
Barbara Kreilkamp wrote:
> Dear SPM-ers,
>
> I am wondering whether you could please help me sort this out, I've got
> a non-brain-extracted T1w_acpc and T2w_acpc image in the same native
> space after running T1w_acpc Segmentation (with MNI normalization) I
> have saved both the forward and inverse deformation field, however, when
> I apply either of these to the T2w_acpc image, the outputted wT2w_acpc
> does not overlap with my wmT1w_acpc.
>
> Thank you very much,
> Best wishes,
> Barbara
>
>
--
____________________________________________________
PD Dr. med. Marko Wilke
Facharzt für Kinder- und Jugendmedizin
Leiter, Experimentelle Pädiatrische Neurobildgebung
Universitäts-Kinderklinik
Abt. III (Neuropädiatrie)
Marko Wilke, MD, PhD
Pediatrician
Head, Experimental Pediatric Neuroimaging
University Children's Hospital
Dept. III (Pediatric Neurology)
Hoppe-Seyler-Str. 1
D - 72076 Tübingen, Germany
Tel. +49 7071 29-83416
Fax +49 7071 29-5473
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http://www.medizin.uni-tuebingen.de/kinder/epn/
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