I would try the Wide Research Molecular Replacement at SBGrid. It may not be the most elegant solution, but it should work if it’s going to work at all…
Frank
> On Nov 16, 2015, at 9:35 AM, Graeme Winter <[log in to unmask]> wrote:
>
> Hi Folks
>
> An unusual question for you: if I have an electron density map, is there a way to search the PDB for structures which match it? i.e. they may be in a different space group etc but I would like to see if the fold is known *with no sequence information*. Ideally searching by 3D homology with a C-alpha trace or something would be ideal.
>
> Is there a way to do it? I appreciate that this is rather back to front with respect to the usual problem, more kin to an inverse phase problem :)
>
> Context: I have an old data set lying around which phases nicely does not match any known unit cell in the PDB; I want to find out what it is without having to sequence by hand
>
> best wishes Graeme
>
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