Complex Trait Analysis of Next Generation Sequence Data Course
July 4-8, 2016
Max Delbrück Center (MDC) for Molecular Medicine
Berlin, Germany
The second annual course on Complex Trait Analysis of Next Generation Sequence Data will be held at the MDC in Berlin from July 4-8, 2016. The goal of the course is to teach the course participants both the theory and application of methods to analyze next generation sequence (NGS) data for human complex traits. Attendees will learn how to design studies, call variants from NGS data, analysis of population- and trio- based sequence data and evaluation of variant functionality. Analyses will include performing complex trait rare variant association analysis for population and trio data. Exercises will be carried out using a variety of computer programs (GATK, IGV, Polyphen2, PSEQ, SEQPower, and Variant Association Tools (VAT)). TOPICS will be include: sequence alignment, calling variants from NGS data, quality control of NGS data, association testing framework for quantitative and qualitative traits (fixed effects, random effects and mixed models), rare variant association methods, estimating power and sample size for rare variant association studies, imputation of rare variants and evaluating variant functionality.
The instructors for the course are Suzanne Leal<https://www.bcm.edu/research/labs/center-for-statistical-genetics/> (Baylor College of Medicine) and Michael Nothnagel<http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/> (University of Cologne).
Application Deadline April 15, 2016
For additional information, course schedule and application form please visit the course website: https://statgen.research.bcm.edu/ComplexNGS2016/view
Now also accepting applications for two additional courses in Berlin at the MDC
Genetic Association Course: With Application to the Analysis of Sequence and Genotype Data
September 5-9, 2016
https://statgen.research.bcm.edu/Genassoc2016/view
Identifying Genes for Mendelian Traits using Next Generation Sequence Data Course
October 31-November 4, 2016
https://statgen.research.bcm.edu/NGSMendelian2016/view
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Suzanne M. Leal, Ph.D.
Professor
Director, Center for Statistical Genetics
Department of Molecular and Human Genetics
Baylor College of Medicine
One Baylor Plaza, 700D
Houston, TX 77030
Tel 1 713 798-4011
Fax 1 713 798-4012
e-mail: [log in to unmask]
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URL: www.bcm.edu/genetics/leal
Administrative Assistant, Francoise Caro
Tel 1 713 798 8212
e-mail: [log in to unmask]
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