Hi Yan,
If you load your map as an mtz into Coot, you can use on-the-fly map sharpening (Calculate>Map Sharpening) to determine the optimal level of sharpening for your local region, and then use this to guide the B-factor used during postprocessing.
Best wishes,
Alan
On 13 Oct 2015, at 18:53, Yan Zhang <[log in to unmask]> wrote:
> Hi all,
>
> I was wondering is there a way to apply B-factor according to local resolution rather than one universal B-factor to whole map during post-processing?
>
> Thanks for your attention.
> Yan
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