Dear Prerana,
I would recommend the The Hampton Additive Screen:
[https://hamptonresearch.com/product_detail.aspx?cid=30&sid=36&pid=27]
[https://hamptonresearch.com/documents/product/hr005595_additive_screen_documents.pdf]
I had a similar problem with small crystals and weak diffraction. In my
case size did matter and larger crystals gave me higher resolution. I
got several larger/better crystals using the Additive Screen.
Steven Herron
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On 9/1/2015 12:27 AM, Prerana G. wrote:
> Dear all,
>
> I am working on a protein (~36kDa) which forms small crystals which
> diffracts at very low resolution. Protein concentration that I have
> used for crystallization is approx. 8mg/ml. I have already tried
> seeding though the improvement in size of the crystal was minimal. I
> have attached the picture of the protein crystal.
>
> How can I improve upon the size of the crystal?
>
>
> Prerana
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