Dear all,
I am looking in the literature for a review and/or a survey discussing the percentage of asymmetric unit initially placed by MR which then primed model building and refinement and ended with structure completion and full structure determination.
I am well aware that the most sensible answer to this question is: IT DEPENDS (on quality of the initial model, NCS, solvent content, etc etc etc.)
I guess I am thinking of an ideal case of a 1:1 AB complex in which we have no-NCS, an average solvent content, no experimental phases and say an AB complex of which we can place A very accurately by MR. What is the ratio of A:B size that will allow tracing of B based on initial MR phases for A?
In absence of a survey, examples from one's or one's friends' research will be also welcome - provided the examples have been published and can be cited.
Thanks
Pietro
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Dr. Pietro Roversi
Oxford University Biochemistry Department - Glycobiology Division
South Parks Road
Oxford OX1 3QU England - UK
Tel. 0044 1865 275339
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