SPM Experts,
I noticed that in the new version of SPM (SPM12), the segmentation module no longer allows for one to enter a mask image (as in SPM8). May I ask why this change was made and how the process is different now? My question stems from the fact that I work with data that has lesions (multiple sclerosis), which significantly affect segmentation. Therefore, it is important that I account for lesions during segmentation, which I had hoped to do by including a binary lesion map as a "mask image" in the segmentation step. However, since this option is no longer available, how might I account for the lesions during segmentation, or does the new segmentation process in SPM12 take issues like this into account? Any information you can provide about the background/rationale of this change and how it may account damage in brains would be greatly appreciated!
Thank you!
Cristina
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