I am not sure what exactly it is you are planning to do but you could
take a look at http://www.ncbi.nlm.nih.gov/pubmed/22530053 ; this was
done on fMRI but you could conceivably do something similar for VBM. I
am not sure, though, that you can draw inferences from effect size on
the method for multiple comparison correction (as this will depend on
several other factors), but I may have gotten that wrong.
M Kate wrote:
> Hi SPM list,
> I have performed a VBM study using a liberal threshold (p<0.001 with
> minimum cluster 100 voxels) and found several clusters.
> Now I would like to do a calculation to examine how many subjects I
> would need to find these effects with a more stringent correction for
> multiple comparisons. So basically a sample size calculation, based on
> the effect size found in this first study.
> Please let me know if you have any thoughts on how to do this. I could
> not find much on the SPM list.
> Thanks in advance for any input.
PD Dr. med. Marko Wilke
Facharzt für Kinder- und Jugendmedizin
Leiter, Experimentelle Pädiatrische Neurobildgebung
Abt. III (Neuropädiatrie)
Marko Wilke, MD, PhD
Head, Experimental Pediatric Neuroimaging
University Children's Hospital
Dept. III (Pediatric Neurology)
D - 72076 Tübingen, Germany
Tel. +49 7071 29-83416
Fax +49 7071 29-5473
[log in to unmask]